Detalhe da pesquisa
1.
Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design.
Annu Rev Biochem
; 87: 451-478, 2018 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29570352
2.
Conformational changes of elongation factor G on the ribosome during tRNA translocation.
Cell
; 160(1-2): 219-27, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25594181
3.
The hexameric helicase DnaB adopts a nonplanar conformation during translocation.
Cell
; 151(2): 267-77, 2012 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23022319
4.
Crystal structures of the E. coli transcription initiation complexes with a complete bubble.
Mol Cell
; 58(3): 534-40, 2015 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25866247
5.
Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.
Mol Cell
; 58(5): 832-44, 2015 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26028538
6.
Negamycin interferes with decoding and translocation by simultaneous interaction with rRNA and tRNA.
Mol Cell
; 56(4): 541-50, 2014 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25306922
7.
Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol Cell
; 56(4): 531-40, 2014 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25306919
8.
Crystal structure of the DENR-MCT-1 complex revealed zinc-binding site essential for heterodimer formation.
Proc Natl Acad Sci U S A
; 116(2): 528-533, 2019 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30584092
9.
The mechanism of E. coli RNA polymerase regulation by ppGpp is suggested by the structure of their complex.
Mol Cell
; 50(3): 430-6, 2013 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23623685
10.
Molecular dynamics analysis of Mg2+ -dependent cleavage of a pistol ribozyme reveals a fail-safe secondary ion for catalysis.
J Comput Chem
; 41(14): 1345-1352, 2020 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32091136
11.
A structural understanding of the dynamic ribosome machine.
Nat Rev Mol Cell Biol
; 9(3): 242-53, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18292779
12.
Crystal structure of Pistol, a class of self-cleaving ribozyme.
Proc Natl Acad Sci U S A
; 114(5): 1021-1026, 2017 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28096403
13.
The initiation of mammalian protein synthesis and mRNA scanning mechanism.
Nature
; 500(7462): 307-11, 2013 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23873042
14.
Structural insights into NusG regulating transcription elongation.
Nucleic Acids Res
; 45(2): 968-974, 2017 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27899640
15.
Structures of E. coli σS-transcription initiation complexes provide new insights into polymerase mechanism.
Proc Natl Acad Sci U S A
; 113(15): 4051-6, 2016 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27035955
16.
Elongation factor 4 remodels the A-site tRNA on the ribosome.
Proc Natl Acad Sci U S A
; 113(18): 4994-9, 2016 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27092003
17.
Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome.
Nucleic Acids Res
; 44(10): 4978-87, 2016 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27079977
18.
Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition.
Nucleic Acids Res
; 44(5): 2439-50, 2016 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26809677
19.
Structural basis for transcription reactivation by RapA.
Proc Natl Acad Sci U S A
; 112(7): 2006-10, 2015 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25646438
20.
Structural basis for the fast self-cleavage reaction catalyzed by the twister ribozyme.
Proc Natl Acad Sci U S A
; 111(36): 13028-33, 2014 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25157168